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Purified anti-mouse IDO

Purified anti-mouse IDO

Cat no: 122402

Supplier: BioLegend
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The mIDO-48 monoclonal antibody recognizes mouse IDO also known as Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, and Indoleamine-pyrrole 2,3-dioxygenase. This antibody does not appear to react with human IDO. IDO is a ubiquitously expressed cytoplasm protein with a predicted molecular weight approximately 45 kD. Indoleamine 2,3-dioxygenase (IDO) is one the best known IFN-gamma inducible genes. The product of IDO gene catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated in protection against intracellular and extracellular pathogens. It also has been shown to maintain the special immune suppressive status of immune-privileged sites such as the brain, eyes, kidney, and placenta. The IDO antibody has been shown to be useful for western blotting and Immunohistochemistry.
Catalogue number: 122402
Reactivities: Mouse
Hosts: Rat
Applications: Immunohistochemistry, Western Blot
Size: 100 microg
Clone: mIDO-48
Gene: 15930
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10-20 microg per 5 ml antibody dilution buffer for each mini-gel. For immunohistochemical staining of frozen sections, the suggested use of this reagent is 4 to 10 microg/ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Recombinant mouse IDO protein
Isotype: Rat IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase
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