Purified anti-mouse LPAM-1 (Integrin alpha4beta7)

Cat no: 120602

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

DATK32 antibody is specific for a combinatorial determinate of integrin alpha4beta7complex. Integrin alpha4beta7 is composed of a 150 kD (alpha4 or CD49d) and a 130 kD (beta7) heterodimer, also known as CD49d/beta7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin alpha4beta7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.

Catalogue number:	120602
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size:	500 microg
Clone:	DATK32
Gene:	16401
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	TK1 cells
Isotype:	Rat IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	alpha4beta7 Integrin, CD49d/beta7, LPAM-1