Purified anti-mouse PDC-TREM

Cat no: 139202

Supplier: BioLegend

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Description
Additional Information

PDC-TREM, also known as plasmacytoid dendritic cell (PDC) -specific receptor, is a member of the TREM receptor family. It is a transmembrane protein composed of an extracellular region with one V-type Ig domain, a transmembrane region with a lysine residue, and a cytoplasmic domain with no recognized signaling motifs. The lysine present in the transmembrane region allows PDC-TREM to form a complex with DAP12 and Plexin-A1. PI3K and Erk 1/2 are involved in the signal transduction of this complex. PDC-TREM is expressed in TLR-activated PDCs and is involved in the production of IFN-alpha.

Catalogue number:	139202
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry, Western Blot
Size:	100 microg
Clone:	4A6
Gene:	328830
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Recombinant soluble PDC-TREM
Isotype:	Rat IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Plasmacytoid dendritic cell-specific receptor