Purified anti-mouse/rat IL-1beta

Cat no: 503501

Supplier: BioLegend

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Description
Additional Information

IL-1 refers to two proteins, IL-1alpha and IL-1beta which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1beta is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. The B122 antibody reacts with the precursor and mature secreted forms of mouse IL-1beta. This antibody also recognizes rat IL-1beta. The B122 antibody can neutralize the bioactivity of natural or recombinant IL-1beta.

Catalogue number:	503501
Reactivities:	Mouse, Rat
Hosts:	Hamster
Applications:	Immunohistochemistry, Immunoprecipitation, Western Blot
Size:	50 microg
Clone:	B122
Gene:	16176
Dilutions:	Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 2-6 microg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-1beta recombinant protein ranging from 2000 to 30 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	E. coli -expressed, recombinant mouse IL-1beta
Isotype:	Armenian Hamster IgG
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Interleukin-1beta, Catabolin, H1, IFNbeta-inducing factor, OAF