Purified anti-mouse Siglec H

Cat no: 129602

Supplier: BioLegend

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Description
Additional Information

The Siglec-H is a member of CD33-related Siglec family which mostly expressed in the innate immune system. Siglec-H is reported to be specifically expressed on plasmacytoid dendritic cells. Siglec-H depends on adaptor protein DAP 12 (DNAX-activating protein of 12 kD) for surface expression and signal transduction. Cross-linking with this antibody can selectively inhibit interferon-alpha production by IPCs following TLR9 ligation.

Catalogue number:	129602
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry
Size:	500 microg
Clone:	551
Gene:	233274
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Siglec-H-Fc recombinant fusion protein
Isotype:	Rat IgG1
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Siglec-H, Sialic acid-binding immunoglobulin-like lectin