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Purified anti-mouse TCR gamma/delta

Purified anti-mouse TCR gamma/delta

Cat no: 107502

Supplier: BioLegend
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T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR alpha/beta) or a gamma and a delta chain (TCR gamma/delta). TCR gamma/delta belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR gamma/delta associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most gamma/delta T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR gamma/delta have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that gamma/delta T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-gamma/delta-bearing T cells in vitro, and to deplete peripheral TCR-gamma/delta-bearing T cells in vivo.
Catalogue number: 107502
Reactivities: Mouse
Hosts: Hamster
Applications: Flow Cytometry, Immunoprecipitation
Size: 500 microg
Clone: UC7-13D5
Gene: 110066,110067
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Isotype: Armenian Hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: T cell receptor gamma/delta, g/d TCR, TCR-g/d
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