Purified anti-mouse TCR Vbeta8.1, 8.2

Cat no: 140102

Supplier: BioLegend

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Description
Additional Information

Vbeta8 T cell receptor (TCR Vbeta8) subfamily has three members, Vbeta8.1, 8.2, and 8.3. These subfamily members are variants of the TCR beta chain that along with the TCR alpha chain forms the TCR heterodimer, responsible for the recognition of peptides presented by the MHC molecules. Murine Vbeta8+ T cells recognize the superantigen staphylococcal enterotoxin B (SEB); in vivo administration of SEB results in the negative selection of Vbeta8+ cells in the thymus. Vbeta8 is one of the most frequently found beta chains on the infiltrating T cells in the brain of mice with experimental autoimmune encephalomyelitis (EAE), and on the T cells response to Toxoplasma gondii.

Catalogue number:	140102
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 microg
Clone:	MR5-2
Gene:	21577
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	H-Y specific TH Clone OI6
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Vbeta8 T-cell receptor, T cell receptor beta 8