The TX17.10 monoclonal antibody recognizes the mouse protein TMTSP also known as THSD1, thrombospondin type-1 domain-containing protein, and transmembrane molecule with thrombospondin module. Mouse TMTSP has a predicted molecular weight of approximately 95 kD. TMTSP is a single pass, Type I transmembrane receptor that contains 1 thrombospondin-like domain. TMTSP is expressed on primitive hematopoietic stem cells and endothelial cells, but to date the function of this protein is unknown. The TX17.10 antibody has been shown to be useful for the detection of mouse TMTSP by flow cytometry, Western blotting, immunoprecipitation, and immunocytochemistry.