Purified anti-mTOR Phospho (Ser2481)

Cat no: 651701

Supplier: BioLegend

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Description
Additional Information

mTOR (mammalian target of rapamycin) is a Ser/Thr kinase acting as an ATP sensor and is reported to autophosphorylate Ser2481 in the presence of sufficient nutrients. Activated mTOR phosphorylates ribosomal protein S6 kinase 1 (S6K1) and the eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) in response to PI3K/Akt signaling, in turn, promoting cell growth, survival, and proliferation.

Catalogue number:	651701
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	50 microl
Clone:	Poly6517
Gene:	2475
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at -20C.
Antigen:	Modified synthetic peptide
Isotype:	Rabbit Ig
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	Mammalian target of rapamycin (mTOR), RAPT1, FK506 binding protein 12-rapamycin associated protein 1 (FRAP1)