Purified anti-p63 (deltaN)

Cat no: 619002

Supplier: BioLegend

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Description
Additional Information

p63 (deltaN) is a member of the p53 family. This protein has multiple isoforms TA p63-alpha, -beta, gamma, deltaN p63-alpha, -beta, and -gamma. The molecular weights of the p63 isoforms alpha=66 kD, beta=52 kD, and gamma=45 kD. This nuclear protein is essential for limb formation, epidermal morphogenesis, and epithelial stem cell regeneration. deltaN isoforms are antagonistic to p53; TA isoforms can transactivate p53 targets. The p63 deltaN isoforms repress TA isoforms; mutant p53 abrogates p63 transactivation. This protein interacts with p53, p73, and the various TA- and deltaN isoforms. The Poly6190 antibody recognizes human p63 deltaN isoforms and has been shown to be useful for Western blotting.

Catalogue number:	619002
Hosts:	Rabbit
Applications:	Immunofluorescence, Western Blot
Size:	200 microl
Clone:	Poly6190
Gene:	8626
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Modified peptide
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	p63, Isoforms TA p63-alpha, -beta, -gamma, deltaN p63-alpha, -beta, -gamma