Purified anti-p90 Rsk

p90 Rsk (ribosomal protein S6 kinase) is a 90 serine/threonine kinase and a member of the S6 kinase subfamily. This kinase is normally cytosolic but is transiently targeted to the membrane after activation. p90 Rsk phosphorylates a range of substrates including ribosomal protein S6 and is activated by the extracellular signal kinases ERK 1/2, PDK-1,and MAPK kinase cascade. p90 Rsk is phosphorylated and can interact with 14-3-3 beta, and ERK 1/2 under quiescent conditions p90 Rsk is decreased upon mitogen stimulation. The Poly6048 antibody recognizes the N-terminal region of human p90 Rsk and has been shown to be useful for Western blotting.

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SPECIFICATIONS

Catalog Number

604802

Size

200 microl

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Clone

Poly6048

Antigen

Recombinant (partial), N-terminal

Gene Id

20111

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

90 kD ribosomal protein S6 kinase, ribosomal S6 kinase 1, RSK-1

Regulatory Status

RUO