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Purified anti-PARC (H7AP1)

Purified anti-PARC (H7AP1)

Cat no: 627602

Supplier: BioLegend
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The PARC protein, also known as p53-associated parkin-like cytoplasmic protein and UbcH7 associated protein 1, is a large (>250 kD) ubiquitously expressed cytoplasmic protein that contains a cullin domain and signature RING-IBR (in-between ring finger domain)-RING domains. PARC is thought to serve as a cytoplasmic anchor in p53-associated complexes thought to be critical in controlling p53 subcellular localization and function. These large complexes that contain PARC, p53 and other associated proteins are approximately 1 MD in non-stressed cells. The PARC protein has been shown to interact with a number of proteins including p53, UBCH8, ubiquitin conjugating enzyme E2G2, and ubiquitin conjugating enzyme E2L3. The P069 monoclonal antibody recognizes human PARC and has been shown to be useful for Western blotting.
Catalogue number: 627602
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Western Blot
Size: 100 microg
Clone: PO69
Gene: 6362
Dilutions: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5 microg per 5 ml antibody dilution buffer (1:500 dilution) for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Human PARC peptide
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: p53-Associated Parkin Like Cytoplasmic Protein, UbcH7 associated protein 1, H7AP1, H7/AP1, KIAA0708
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