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Purified anti-PKCalpha Phospho (Thr638)

Purified anti-PKCalpha Phospho (Thr638)

Cat no: 649101

Supplier: BioLegend
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Protein kinase C alpha (PKCalpha), also known as PRKCA, refers to both a human gene and the protein that is encoded by it. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca2+ handling in myocytes. The purified anti-PKCalpha Phospho (Thr638) antibody detects PKCalpha only when phosphorylated at threonine 638.
Catalogue number: 649101
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 25 microl
Clone: Poly6491
Gene: 24681
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microl antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store frozen at -20C.
Antigen: Modified synthetic peptide
Isotype: Rabbit polyclonal
Clonality: Polyclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: -20 C
Alternative names: AAG6; PKCA; PRKACA; MGC129900; MGC129901; PKC-alpha; PRKCA
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