Purified anti-PLCgamma-1 Phosphorylated (Tyr783)

Cat no: 656202

Supplier: BioLegend

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Description
Additional Information

PLCgamma-1 is a ubiquitously expressed isozyme that is activated by phosphorylation of tyrosine 783. It plays important roles in mammalian growth and development, proliferation, differentiation, signal transduction, endocytosis, cytoskeletal reorganization, and activation of ion channels. In the brain, PLCgamma-1 is highly expressed and participates in brain development and synaptic transmission. Abnormal expression and activation of PLCgamma-1 is associated with various brain disorders such as epilepsy, depression, Huntington's disease and Alzheimer's disease. Research in zebrafish also suggests its important roles in the maturation of granulocytes.

Catalogue number:	656202
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	200 microl
Clone:	Poly6562
Gene:	5335
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 4.0 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at -20C.
Antigen:	KLH conjugated modified synthetic peptide
Isotype:	Rabbit Polyclonal IgG
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	PLCG1, PLC Gamma1, PLCg 1, NCKAP3