Purified anti-rat TCR Vbeta8.2/8.4

Cat no: 201201

Supplier: BioLegend

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Description
Additional Information

The R78 antibody recognizes the specific T cell receptor beta chain Vbeta 8.2/8.4. The TCR beta chain interacts with the TCR alpha chain and CD3 to form an antigen binding and signaling complex. TCR alpha and beta are members of the immunoglobulin superfamily expressed on most peripheral T cells, intestinal epithelial lymphocytes, and thymocytes. TCR Vbeta 8.2/8.4 is expressed on a subset of TCR alpha/beta-bearing T cells. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation. The alpha/beta TCR recognizes peptide bound to MHC class I and II. The R78 antibody is useful for the analysis of T cell receptor repertoire.

Catalogue number:	201201
Reactivities:	Rat
Hosts:	Mouse
Applications:	Flow Cytometry, Immunohistochemistry
Size:	50 microg
Clone:	R78
Gene:	11462
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Rat Vbeta 8.2 TCR-expressing rat/mouse T cell hybrid 56.4
Isotype:	Mouse (BALB/c) IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Vbeta8.2/8.4 TCR