Purified anti-Spt16 (FACT140 complex)

Cat no: 607002

Supplier: BioLegend

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Description
Additional Information

Spt16 is a 120-140 kD nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT140 complex is composed of the Spt16 and the SSRP1 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. The 8D2 monoclonal antibody recognizes human Spt16 and has been shown to be useful for Western blotting.

Catalogue number:	607002
Reactivities:	Human
Hosts:	Mouse
Applications:	Immunofluorescence, Immunoprecipitation, Western Blot
Size:	100 microg
Clone:	8D2
Gene:	852665
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microg per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store at 4C.
Concentration:	0.5 mg/ml
Antigen:	Recombinant (full length)
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Facilitates Chromatin Transcription (FACT140), Spt 16 protein, Cdc68