Purified anti-SSRP1

Cat no: 609702

Supplier: BioLegend

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Description
Additional Information

SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D1 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.

Catalogue number:	609702
Reactivities:	Human
Hosts:	Mouse
Applications:	Immunofluorescence, Immunoprecipitation, Western Blot
Size:	100 microg
Clone:	10D1
Gene:	6749
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microg per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Recombinant (partial) (308-524aa)
Isotype:	Mouse IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Structure specific recognition protein 1 (SSRP1), Facilitates Chromatin Transcription 80 kD subunit, Recombination signal sequence recognition protein