Purified anti-XBP-1s

Cat no: 647501

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of its binding ability to X-box, a conserved transcriptional element in the promoter of human HLA DR gene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is also essential for differentiation of plasma cells. XBP-1 upregulates as part of the ER stress response, also known as the unfolded protein response. Unspliced XBP-1 is 261 amino acids and migrates on the SDS-PAGE around 33 kD; spliced XBP-1, recognized by clone 143F, is371 amino acids and migrates around 55 kD.

Catalogue number:	647501
Reactivities:	Human
Hosts:	Mouse
Applications:	ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Size:	25 microg
Clone:	143F
Gene:	7494
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 to 2 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	XBP-1s recombination protein
Isotype:	Mouse IgG2a
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	X-box binding protein 1