Pyrimethamine

Cat no: 020321

Supplier: United States Biological

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Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial. Melting Point: As Reported Solubility: As Reported Method for Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis TLC Conditions: As Reported Specific Rotation: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:

Catalogue number:	020321
Size:	100mg
Form:	As Reported
Purity:	~90%
Alternative names:	5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine; Chloridin; Chloridine; Daraprim; Khloridin; Malocide; Pirimecidan; Pirimetmin; NSC 3061; RP 4753;
References:	1. Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983). 2. Leport, C., et al.: Am. J. Med., 84, 94 (1988). 3. McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998). 4. Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004).

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Pyrimethamine

Cat no: 020321

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