Protein phosphorylation is a common post-translational modification in eukaryotes. Eukaryotic cell protein phosphorylation is divided into two types: serine (Ser)/threonine (Thr) phosphorylation and tyrosine (Tyr) phosphorylation. Although the proportion of Tyr phosphorylation is small, it plays an extremely important role in the fate of cells and individuals, and is closely related to diseases such as cancer.