R-Spondin 3, Human, BioAssay(TM) DuoSet ELISA Development Kit (Cristin 1, PWTSR, RSPO3, THSD2)

Supplier:

United States Biological

Cat no: 145765

R-Spondin 3, Human, BioAssay(TM) DuoSet ELISA Development Kit (Cristin 1, PWTSR, RSPO3, THSD2)

R-Spondin 3 (RSPO3, Roof plate-specific Spondin 3), also called cysteine-rich and single thrombospondin domain containing-1 (Cristin 1), is an ~31kD secreted protein that shares ~40% aa identity with the other three R-Spondin family members. All are positive modulators of Wnt/beta-Catenin signaling, but each has a distinct expression pattern (1-4). Like other R-Spondins, R-Spondin 3 contains two adjacent cysteine-rich furin-like domains (amino acids (aa) 35-135) with one potential N-glycosylation site (36aa), followed by a thrombospondin (TSP-1) motif (aa147-207) and a region rich in basic residues (aa211-269). Only the furin-like domains are needed for beta-Catenin stabilization. Within aa21-209, mouse R-Spondin 3 shares 93%, 97%, 96%, 95% and 91%

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SPECIFICATIONS

Catalog Number

145765

Size

1Kit

Applications

ELISA

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

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