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RAB34, Recombinant, Human, aa1-259, His-tag (Ras-related Protein Rab-34, Ras-related Protein Rab-39, Ras-related Protein Rah, RAB39, RAH)

Cat no: 029692

RAB34, Recombinant, Human, aa1-259, His-tag (Ras-related Protein Rab-34, Ras-related Protein Rab-39, Ras-related Protein Rah, RAB39, RAH)

RAB34, is localized to the plasma membrane and endocytic compartments and controls a fast endocytic recycling pathway. This protein is involved in protein transport, specifically the redistribution of lysosomes to the peri-Golgi region. In fibroblasts, this protein was colocalized with actin to the membrane ruffles and membranes of relatively large vesicles adjacent to the ruffles.\n\nSource:\nRecombinant corresponding to aa1-259 from human RAB34, fused to His-tag at N-terminal expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MNILAPVRRD RVLAELPQCL RKEAALHGHK DFHPRVTCAC QEHRTGTVGF KISKVIVVGD LSVGKTCLIN RFCKDTFDKN YKATIGVDFE MERFEVLGIP FSLQLWDTAG QERFKCIAST YYRGAQAIII VFNLNDVASL EHTKQWLADA LKENDPSSVL LFLVGSKKDL STPAQYALME KDALQVAQEM KAEYWAVSSL TGENVREFFF RVAALTFEAN VLAELEKSGA RRIGDVVRIN SDDSNLYLTA\nSKKKPTCCP\n\nMolecular Weight:\n~31.2kD (MALDI-TOF)\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

029692

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 40% glycerol, 0.1M sodium chloride, 1mM DTT.

Purity

~90% (SDS-PAGE)

References

1. Sun P. et al. (2003) J Biol Chem. 278:4063-71. 2. Novick P. et al. (1993) Cell. 75: 597-601.

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