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RAB3A, Recombinant, Human, aa1-220, His-tag  (Ras-related Protein Rab-3A)

Cat no: R0006-75H

RAB3A, Recombinant, Human, aa1-220, His-tag (Ras-related Protein Rab-3A)

Rab3A belongs to the small GTPase superfamily, Rab family. It is a small, Ras-like GTPase expressed in neuroendocrine cells, in which it is associated with secretory vesicle membranes and regulates exocytosis. This protein could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Purified by using conventional chromatography techniques.\n\nSource:\nRecombinant corresponding to aa1-220 of human RAB3A, fused to His-tag at N-terminal, expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MASATDSRYG QKESSDQNFD YMFKILIIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTIYRNDKR IKLQIWDTAG QERYRTITTA YYRGAMGFIL MYDITNEESF NAVQDWSTQI KTYSWDNAQV LLVGNKCDME DERVVSSERG RQLADHLGFE \nFFEASAKDNI NVKQTFERLV DVICEKMSES LDTADPAVTG AKQGPQLSDQ QVPPHQDCAC\n\nMolecular Weight: \n~27.1kD (240aa), confirmed by MALDI-TOF\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

R0006-75H

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH8, 0.1M sodium chloride ,1mM DTT, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

Brondyk WH. et al. (1995) Mol Cell Biol.15:1137-1143. Novick P. et al. (1993) Cell. 75:597-601.

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