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Rabbit Anti-ABCG2 monoclonal antibody, clone KG1005

Cat no: CABT-31717RH

Rabbit Anti-ABCG2 monoclonal antibody, clone KG1005

Rabbit Anti-ABCG2 monoclonal antibody for WB, ICC/IF, IHC, FC. ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC half-transporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.

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SPECIFICATIONS

Catalog Number

CABT-31717RH

Hosts

Rabbit

Reactivities

Hum, Mouse

Conjugates

Unconj

Clone

KG1005

Target

ABCG2

Gene Id

196

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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