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Rabbit Anti-ADAM17 monoclonal antibody, clone KN21-46

Rabbit Anti-ADAM17 monoclonal antibody, clone KN21-46

Cat no: DCABH-5885

Supplier: Creative Diagnostics
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Rabbit Anti-ADAM17 monoclonal antibody for WB, ICC/IF, IP, FC. Tumor necrosis factor ? (TNF?), also known as lymphotoxin, is a pleiotropic cytokine. TNF?, also known as cachetin, is a cytokine that binds to the same receptors, producing an array of effects similar to those of TNF?. TNF? and TNF? share 30% amino acid homology and have similar biological activities. TNF? is produced by activated lymphocytes, including CD4+ T helper cell type 1 lymphocytes, CD8+ lymphocytes and certain B lymphoblastoid cell lines. TNF? is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNF? and TNF? can modulate many immune and inflammatory functions while having the ability to inhibit tumor growth. TACE (for TNF? converting enzyme) is a metalloproteinase that cleaves the membrane-bound TNF? precursor to release soluble TNF?.
Catalogue number: DCABH-5885
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KN21-46
Gene: 64919
Target: ADAM17
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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