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Rabbit Anti-AIFM1 monoclonal antibody, clone TA06-12

Rabbit Anti-AIFM1 monoclonal antibody, clone TA06-12

Cat no: CABT-L595

Supplier: Creative Diagnostics
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Rabbit Anti-AIFM1 monoclonal antibody for WB, ICC, IHC, IP, FC. A key event in the apoptotic process is the opening of the mitochondrial permeability transition pore, an event that is regulated by Bcl-2 family proteins, resulting in the release of several proteins from the mitochondrial intermembrane space. Several of these proteins participate in apoptosis, including cytochrome c, procaspases 2, 3, and 9, and AIF (apoptosis-inducing factor). AIF has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIF from mitochondria, but not to block its apoptogenic activity.
Catalogue number: CABT-L595
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TA06-12
Gene: 838
Target: AIFM1
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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