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Rabbit Anti-BPI monoclonal antibody, clone TO17-74

Rabbit Anti-BPI monoclonal antibody, clone TO17-74

Cat no: DCABH-6134

Supplier: Creative Diagnostics
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Rabbit Anti-BPI monoclonal antibody for WB, FC. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). The 31.5-kb-long human BPI gene maps to chromosome 20q11.23-q12, contains 15 exons, and encodes a 456 amino acid protein. Epithelial cells which line mucosal surfaces are the first line of defense against bacterial invasion and infection. BPI localizes to the cell surface of epithelial cells and blocks endotoxin-mediated signaling, thereby protecting mucosal surfaces against gram-negative bacteria and their endotoxin. BPI, lipopolysaccharide binding protein (LBP), phospholipid transfer protein (PLTP), and cholesteryl ester transfer protein (CETP) constitutes a family of functionally related proteins.
Catalogue number: DCABH-6134
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TO17-74
Gene: 3297
Target: BPI
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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