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Rabbit Anti-Calbindin monoclonal antibody, clone KG16-12

Cat no: CABT-L879

Rabbit Anti-Calbindin monoclonal antibody, clone KG16-12

Rabbit Anti-Calbindin monoclonal antibody for WB, ICC/IF, IHC. The family of EF-hand type Ca-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 ? and ?, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin ? and Parvalbumin ? (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261 amino acid protein with six EF-hand domains, four of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

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SPECIFICATIONS

Catalog Number

CABT-L879

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

KG16-12

Target

Calbindin

Gene Id

3635

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

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