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Rabbit Anti-CALR monoclonal antibody, clone TV48-14

Rabbit Anti-CALR monoclonal antibody, clone TV48-14

Cat no: DCABH-139

Supplier: Creative Diagnostics
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Rabbit Anti-CALR monoclonal antibody for WB, ICC/IF, IHC, IP, FC. Calnexin and calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor calregulin contains the calcium-binding "E-F hand" motif found in calmodulins. Calnexin and calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.
Catalogue number: DCABH-139
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TV48-14
Gene: 3663
Target: CALR
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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