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Rabbit Anti-CARD11 monoclonal antibody, clone C.583.4

Cat no: CABT-L1216

Rabbit Anti-CARD11 monoclonal antibody, clone C.583.4

Rabbit Anti-CARD11 monoclonal antibody for WB. The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

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SPECIFICATIONS

Catalog Number

CABT-L1216

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

C.583.4

Target

CARD11

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

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