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Rabbit Anti-CD20 monoclonal antibody, clone TZ23-12

Cat no: CABT-L610

Rabbit Anti-CD20 monoclonal antibody, clone TZ23-12

Rabbit Anti-CD20 monoclonal antibody for WB, IHC, IP. CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors.

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SPECIFICATIONS

Catalog Number

CABT-L610

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TZ23-12

Target

CD20

Gene Id

4602

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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