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Rabbit Anti-CD20 monoclonal antibody, clone TZ23-12

Rabbit Anti-CD20 monoclonal antibody, clone TZ23-12

Cat no: CABT-L610

Supplier: Creative Diagnostics
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Rabbit Anti-CD20 monoclonal antibody for WB, IHC, IP. CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors.
Catalogue number: CABT-L610
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TZ23-12
Gene: 4602
Target: CD20
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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