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Rabbit Anti-CDK5 monoclonal antibody, clone TS40-12

Rabbit Anti-CDK5 monoclonal antibody, clone TS40-12

Cat no: CABT-L576

Supplier: Creative Diagnostics
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Rabbit Anti-CDK5 monoclonal antibody for WB, IHC, IP, FC. Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2-Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. Cdk5 is thought to be involved in the G1-S transition of the cell cycle and is highly expressed in mature neurons. Activity of Cdk5 increases significantly during neuronal differentiation. Cdk5 has been postulated to be a neurofilament or tau protein kinase, based on its ability to phosphorylate these proteins in vitro.
Catalogue number: CABT-L576
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TS40-12
Gene: 6667
Target: CDK5
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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