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Rabbit Anti-CR2 monoclonal antibody, clone TD1792

Cat no: DCABH-3596

Rabbit Anti-CR2 monoclonal antibody, clone TD1792

Rabbit Anti-CR2 monoclonal antibody for WB, ICC, IHC, IP, FC. CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.

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SPECIFICATIONS

Catalog Number

DCABH-3596

Hosts

Rabbit

Reactivities

Hum, Mouse

Conjugates

Unconj

Clone

TD1792

Target

CR2

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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