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Rabbit Anti-DAXX monoclonal antibody, clone L.290.4

Cat no: CABT-L1265

Rabbit Anti-DAXX monoclonal antibody, clone L.290.4

Rabbit Anti-DAXX monoclonal antibody for ICC, IF, WB. This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

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SPECIFICATIONS

Catalog Number

CABT-L1265

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov

Conjugates

Unconj

Clone

L.290.4

Target

DAXX

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

SUPPLIER INFO

Creative Diagnostics

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