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Rabbit Anti-FLNA monoclonal antibody, clone TB41-19

Cat no: CABT-L571

Rabbit Anti-FLNA monoclonal antibody, clone TB41-19

Rabbit Anti-FLNA monoclonal antibody for WB, ICC/IF, IHC, FC. Caldesmon, Filamin 1, Nebulin and Villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in non-muscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of Nebulin are produced by alternative exon usage. Villin is Ca2-regulated and is the major structural component of the brush border of absorptive cells.

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SPECIFICATIONS

Catalog Number

CABT-L571

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

TB41-19

Target

FLNA

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

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