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Rabbit Anti-Human ABCB1 Polyclonal Antibody

Cat no: DPABH-02400

Rabbit Anti-Human ABCB1 Polyclonal Antibody

Rabbit Anti-Human ABCB1 Polyclonal Antibody for IHC, ICC-IF. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

DPABH-02400

Hosts

Rabbit

Reactivities

Hum

Target

ABCB1

Gene Id

5243

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at +4В°C for short term storage. Long time storage is recommended at -20В°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

SUPPLIER INFO

Creative Diagnostics

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