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Rabbit Anti-Human ABL1 polyclonal antibody

Rabbit Anti-Human ABL1 polyclonal antibody

Cat no: CABT-L1696

Supplier: Creative Diagnostics
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Rabbit Anti-Human ABL1 polyclonal antibody for IHC-P. The c-Abl proto-oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c-Abl proto-oncogene undergoes a (9; 22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) ; as the result of the fusion of c-Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.
Catalogue number: CABT-L1696
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 25
Target: ABL1
Isotype: IgG
Clonality: Polyclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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