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Rabbit Anti-Human AGR2 monoclonal antibody, clone TO85-12

Rabbit Anti-Human AGR2 monoclonal antibody, clone TO85-12

Cat no: DCABH-3616

Supplier: Creative Diagnostics
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Rabbit Anti-Human AGR2 monoclonal antibody for WB, ICC, IHC, IP, FC. AGR2 (Anterior Gradient Protein 2), also known as AG2, GOB-4 or HAG-2, is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and ?-dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.
Catalogue number: DCABH-3616
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TO85-12
Gene: 10551
Target: AGR2
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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