Rabbit Anti-Human AGT Polyclonal Antibody

Rabbit Anti-Human AGT Polyclonal Antibody for IHC, WB. The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

DPABH-28529

Hosts

Rabbit

Reactivities

Hum

Target

AGT

Gene Id

183

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at +4В°C for short term storage. Long time storage is recommended at -20В°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.