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Rabbit Anti-Human AMPK alpha-1 (phospho Thr172) monoclonal antibody, clone 20I3M30

Rabbit Anti-Human AMPK alpha-1 (phospho Thr172) monoclonal antibody, clone 20I3M30

Cat no: CABT-L1543

Supplier: Creative Diagnostics
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Rabbit Anti-Human AMPK alpha-1 (phospho Thr172) monoclonal antibody for ICC, IF, WB. AMPKa belongs to the family of AMP activated protein kinases, that plays a central role in regulating cellular and organismal energy balance in response to the balance between AMP/ATP, and intracellular Ca2+ levels. AMPK exists as a heterotrimer comprising of catalytic alpha subunit, and regulatory beta and gamma subunits. The alpha subunit is activated by increases in the cellular AMP:ATP ratio caused by metabolic stresses, and can mediate the effects of the adipokines leptin and adiponectin. Two isoforms differ in subcellular localization and AMP-dependence. Phosphorylation of threonine 172 in the alpha subunit is a key determinant of AMPK activity.
Catalogue number: CABT-L1543
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 20I3M30
Gene: 5562
Target: PRKAA1
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

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