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Rabbit Anti-Human APBB1 Polyclonal Antibody

Cat no: DPABH-06593

Rabbit Anti-Human APBB1 Polyclonal Antibody

Rabbit Anti-Human APBB1 Polyclonal Antibody for IHC, WB. The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimers disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene products nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimers disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]

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SPECIFICATIONS

Catalog Number

DPABH-06593

Hosts

Rabbit

Reactivities

Hum

Target

APBB1

Gene Id

322

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at +4В°C for short term storage. Long time storage is recommended at -20В°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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