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Rabbit Anti-Human ATG14 monoclonal antibody, clone 20I30M25

Rabbit Anti-Human ATG14 monoclonal antibody, clone 20I30M25

Cat no: CABT-L1201

Supplier: Creative Diagnostics
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Rabbit Anti-Human ATG14 monoclonal antibody for ICC, IF, WB. ATG14 (Autophagy related protein homolog 14) is encoded by the ATG14 gene and is located on chromosome 14 in humans. It is also known as ATG14L or BARkOR (Beclin 1-associated autophagy-related key regulator). Autophagy is an evolutionarily conserved process that involves recycling of misfolded cellular proteins and degradation of dysfunctional organelles. Autophagy is induced as a cellular response to nutrient stress which includes the formation of autophagosomes, fusion of these with the lysosome and formation of the autophagolysosome. The Class III PI3-kinase, Vps34 and its interacting partner Beclin 1 have been shown to form a complex which specifically includes ATG 14 (type 1) or UVRAG (type 2). Atg 14 guides the type 1 complex to the preautophagosomal structure (PAS) and is critical for the initiation of autophagosome formation.
Catalogue number: CABT-L1201
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 20I30M25
Gene: 22863
Target: ATG14
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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