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Rabbit Anti-Human ATG4B monoclonal antibody, clone 2ID7MD20

Rabbit Anti-Human ATG4B monoclonal antibody, clone 2ID7MD20

Cat no: CABT-L1203

Supplier: Creative Diagnostics
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Rabbit Anti-Human ATG4B monoclonal antibody for FC, ICC, IHC-P, IF, WB. Cysteine protease ATG4b is an enzyme which is coded by ATG4b gene. Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and protein. ATG4b is a deubiquitin-like protease that plays dual roles in the core machinery of autophagy. ATG4b, cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. ATG4b is mainly expressed in the skeletal muscle, brain, heart, liver and pancreas.
Catalogue number: CABT-L1203
Reactivities: Human, Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 2ID7MD20
Gene: 23192
Target: ATG4B
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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