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Rabbit Anti-Human BCL2L11 monoclonal antibody, clone TV1429

Cat no: CABT-L638


Supplier: Creative Diagnostics
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Rabbit Anti-Human BCL2L11 monoclonal antibody for WB, ICC, IHC, IP. Pro-apototic Bcl-2 family members promote cell death by neutralizing their anti-apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins, and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long). ERK1/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1/2 phosphorylation exist on BimEL, whereas ERK1/2 does not effect BimS and BimL, implying a unique role for BimEL in cell survival signaling.
Catalogue number: CABT-L638
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TV1429
Gene: 10018
Target: BCL2L11
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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