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Rabbit Anti-Human beta Catenin monoclonal antibody, clone F358

Rabbit Anti-Human beta Catenin monoclonal antibody, clone F358

Cat no: CABT-L1257

Supplier: Creative Diagnostics
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Rabbit Anti-Human beta Catenin monoclonal antibody for IHC-P. The catenins (alpha, beta and gamma) are ubiquitously expressed, cytoplasmic proteins associated with E-cadherin at cellular junctions. beta-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between alpha-actinin and alpha-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion. Mutations in the catenin gene, CTNNB1, have been implicated in its accumulation and various forms of carcinomas.
Catalogue number: CABT-L1257
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: F358
Gene: 1499
Target: CTNNB1
Isotype: IgG
Clonality: Monoclonal
Storage temp: 4°C

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