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Rabbit Anti-Human Bim monoclonal antibody, clone 9I2M5

Cat no: CABT-L1208

Rabbit Anti-Human Bim monoclonal antibody, clone 9I2M5

Rabbit Anti-Human Bim monoclonal antibody for FC, WB. BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

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SPECIFICATIONS

Catalog Number

CABT-L1208

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

9I2M5

Target

BCL2L11

Gene Id

10018

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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