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Rabbit Anti-Human BNIP3L polyclonal antibody

Rabbit Anti-Human BNIP3L polyclonal antibody

Cat no: CABT-L1703

Supplier: Creative Diagnostics
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Rabbit Anti-Human BNIP3L polyclonal antibody for IHC-P. Members in the BCL-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including BAD, BAX, BID, BIK, HRK, NIP3, and BIM, form a growing subclass of the BCL-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3, and NIX (for NIP3-like protein X) . Bnip3L/Bnip3/Nix is a homolog of the E1B 19K/BCL-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppression by BCL-2 and BCL-XL. Bnip3L is localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in human tissues. Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins.
Catalogue number: CABT-L1703
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 665
Target: BNIP3L
Isotype: IgG
Clonality: Polyclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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