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Rabbit Anti-Human CAV2 monoclonal antibody, clone TZ33-16

Cat no: DCABH-1646

Rabbit Anti-Human CAV2 monoclonal antibody, clone TZ33-16

Rabbit Anti-Human CAV2 monoclonal antibody for WB, ICC/IF, IHC, IP. Caveolae (also known as plasmalemmal vesicles) are 50-100 nM flask-shaped membranes that represent a subcompartment of the plasma membrane. On the basis of morphological studies, caveolae have been implicated to function in the transcytosis of various macromolecules (including LDL) across capillary endothelial cells, uptake of small molecules via potocytosis and the compartmentalization of certain signaling molecules including G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 and caveolin-3, have been identified as principal components of caveolae. Two forms of caveolin-1, designated a and b, share a distinct but overlapping cellular distribution and differ by an N-terminal 31 amino acid sequence that is absent from the b isoform. Caveolin-1 shares 31% identity with caveolin-2 and 65% identity with caveolin-3 at the amino acid level. Functionally, the three proteins differ in their interactions with heterotrimeric G protein isoforms.

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SPECIFICATIONS

Catalog Number

DCABH-1646

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TZ33-16

Target

CAV2

Gene Id

858

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

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