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Rabbit Anti-Human CCR3 monoclonal antibody, clone 34I28M2

Cat no: CABT-L1225

Rabbit Anti-Human CCR3 monoclonal antibody, clone 34I28M2

Rabbit Anti-Human CCR3 monoclonal antibody for ICC, IF. Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4. CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates.

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SPECIFICATIONS

Catalog Number

CABT-L1225

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

34I28M2

Target

CCR3

Gene Id

1232

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C, Avoid Freeze/Thaw Cycles

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