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Rabbit Anti-Human CD19 monoclonal antibody, clone KG211-17

Cat no: CABT-L898


Supplier: Creative Diagnostics
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Rabbit Anti-Human CD19 monoclonal antibody for WB, ICC/IF, IHC. CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is selectively expressed on the cell surface of B-lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK). Expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. CD19 forms functional complexes with B-lymphocyte surface proteins, including integrin b1, CD21 and CD81, which are involved in regulating B-cell development.
Catalogue number: CABT-L898
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KG211-17
Gene: 930
Target: CD19
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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